Get to Know How Marijuana Can Help Autoimmune Disease Patients

It is important to note that although autoimmune diseases do not have a cure, they can be treated in order to make the patient feel better. Patients suffering from fatigue, joint pain, chronic pain, insomnia, and many other symptoms can be treated so that they will begin to feel better. In the body, Cannabis Sativa is a type of plant with molecules that create cannabinoids, chemicals THC and CBD, which might be found in marijuana, start to work the moment they are ingested.

Endocannabinoids are fat-based neurotransmitters. Anandamide and 2-arachidonoylglycerol are two of the most studied. Cannabinoids are substances that enter the body. They find receptors in the body and change how it works. These receptors are called CB1 and CB2. This can affect the chemicals in the body that tell our brain how we feel. It will either increase or decrease these chemicals. This might cause pain, inflammation or changes to other processes in your body. 

Sometimes, when the body does not regulate the endocannabinoid system, it can cause cancer and Alzheimer’s disease. If you want to learn more about the endocannabinoid system working process, You can read more about endocannabinoids on our website.   

Immunosuppression

THC and CBD, the active ingredients in medicinal marijuana, have been found to trigger an immunosuppressive effect. As a result of this, T-LYMPHOCYTES and macrophages die from a lack of oxygen, which is what causes this to work. Cells such as lymphocytes and macrophages fight infections in our bodies by fighting off harmful bacteria. But when an autoimmune disease happens, they can attack healthy tissues. Triggering cell death means that the cells attacking healthy tissue will decrease.

Using cytokines also helps THC to fight inflammation. Cytokines are proteins that send signals to the immune system. Cytokines are in the blood. When they are disrupted, white blood cells slow down and inflammation is decreased.

A study on the effects of cannabis and other drugs on autoimmune diseases and immunosuppression was published in Cannabis and Cannabinoid Research. The study looked at the results from 24 other studies. The researchers discovered that CBD was one of the main activators of immunity after cannabis use in their study. In the presence of CBD (cannabidiol), TH1 and TH17 proinflammatory cells were reduced. Also, the number of pro-inflammatory white blood cells, such as cytokines, interleukin, and interferon, was decreased by this medication.

Researchers also believe that terpenes – naturally occurring chemicals found in plants – help relieve inflammation and pain by interacting with each other in a way that acts alongside non-steroidal anti-inflammatory drugs. Moreover, the researchers found that CBD, cannabigerol (CBG), and other compounds that contain cannabinoids and terpenes can also be effective in helping the body to reduce inflammation. THC works well on its own, but CBD usually helps more. There is a way to use cannabinoids together that will give you more health benefits. It is called the entourage effect.

When you have symptoms of inflammation, medical cannabis can help to ease the symptoms by reducing inflammation in your body. There are many different ways that medical marijuana works, depending on the place in your body where your symptoms occur.

Inflammation of the digestive system

Medical research shows that people with digestive inflammation, like ulcerative colitis and Crohn’s disease, can be helped by marijuana. Marijuana has chemicals in it called endocannabinoids. If you have an autoimmune issue that affects your intestines, your white blood cells known as neutrophils will keep attacking the intestines. P-glycoprotein is a protein that reduces the inflammation of neutrophils. It can be modulated by CB2 receptors from the endocannabinoid system.

Different Treatments for Autoimmune Diseases

To treat an autoimmune disorder, you will need to use cannabis or CBD, depending on the type of autoimmunity and the part of the body where the body attacks itself. It is very important that you check the following conditions, so you will be able to receive information regarding how to deal with the specific symptoms.

  • Psoriasis
  • Arthritis
  • Rheumatoid arthritis
  • Multiple sclerosis
  • Inflammation
  • Chronic pain
  • Insomnia
  • Ulcerative colitis
  • Crohn’s disease
  • Amyotrophic lateral sclerosis (ALS)
  • Diabetes
  • Fibromyalgia
  • Neuropathy
  • Lupus

Important considerations

It’s important to ask your doctor before taking medical marijuana. You need to know if it is safe for you, or if there are any side effects. Some conditions need to be treated differently than others. There are different types of conditions that may need to be treated differently. These conditions are in different places in the body. Treat these diseases when they are small. If they are not checked or treated completely, then the disease may become permanent and damage your body. It is also advised to start with a small dose of medical marijuana and then gradually increase it from there.

Cannabis can have some negative side effects. Some of these include an increase in anxiety, changes in heart rate, and an increase in appetite. Cannabis side effects may occasionally assist you. People do not know how long-term use can affect your health.

Classification of autoimmunity conditions

Autoimmune diseases happen when the body attacks itself. It can cause things like pain, inflammation, and other symptoms. Autoimmune diseases fall into two categories: those in which the immune system attacks something it shouldn’t be attacking, and those in which it doesn’t attack anything at all. Some people get organ-specific autoimmune diseases where your immune system attacks just one part of you. Other people get systemic autoimmune diseases where your whole body is attacked. Here are the types:

  1. Systemic Autoimmune:
  2. Organ-specific: 

The following diseases are systemic autoimmune:

  • Systemic lupus erythematosus (SLE) 
  • Goodpasture’s syndrome 
  • Sarcoidosis 
  • Rheumatoid Arthritis 

The following diseases are organ-specific:

 

Dermatologic diseases

  • Sjögren’s Syndrome 
  • Scleroderma 
  • Psoriasis 
  • Alopecia areata 

Endocrinologic diseases

  • Type 1 diabetes mellitus 
  • Addison’s disease 
  • Hashimoto’s thyroiditis

Neurologic diseases

  • Multiple sclerosis 
  • Myasthenia gravis 

Hematologic diseases

  • Pernicious anemia 
  • Polyarteritis nodosa 

Gastrointestinal diseases

  • Celiac disease 
  • Ulcerative Colitis 
  • Crohn’s disease 

The difference between autoinflammatory and autoimmune diseases

Both autoimmunity and autoinflammatory diseases are problems with the immune system. These disorders are also known as primary immunodeficiencies. People can have PIDs when they have cells that are not working well for the immune system. These cells then attack themselves, which is bad. There are more than 250 different types of PIDs (the number may vary). In this group of patients the immune system is compromised, which makes them more likely to get ill.

Overview of autoimmune diseases 

The body has a way of identifying cells as being foreign. If the body thinks that some of its own cells are foreign, it will attack them. The body then attacks tissues that are usually ignored. It damages many organs and changes how they work. Some people get cancer because of their genes. Other times, bacteria or viruses can cause it.  

Adaptive immunity is impacted when an autoimmune disease occurs. When the body encounters pathogens that it has already encountered, the adaptive immune system remembers them and attacks them. 

Overview of Autoinflammatory diseases

Autoinflammatory diseases are inflammatory disorders that can happen in the absence of an infection. Autoinflammatory diseases happen when the immune system makes inflammation in a person who does not have an antigen.

Autoinflammatory diseases are caused by the body’s natural immunity system attacking its tissues. The innate immune system is your body’s first line of defense when a new or old ailment enters the body. 

*DigiDrs is not offering this as professional medical advice. Do not attempt to self diagnose, or prescribe treatment based on the information provided in these pages. Consult a physician before making decisions on the treatment of any of these medical conditions.

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