Medical Cannabis and Fibrous Dysplasia
Fibrous dysplasia is a condition in which excessive connective tissue grows over diseased cartilage. The bone disease causes pain and fractures, according to the US National Health Institute of Arthritis and Musculoskeletal and Skin Diseases. The condition develops as a result of an altered gene mutation, which may affect either one bone or many bones.
Medical cannabis has been shown by law and research to ease symptoms of different conditions. This is because its properties have a positive effect on the ailments it is used to treat. Fibrous dysplasia was added to the list of qualifying conditions for medical cannabis by Governor J.B. Pritzker in January of 2020.
Symptoms, Causes, and Treatment of Fibrous Dysplasia
The NIH adds that while fibrous dysplasia is not distinguished by age, the disease’s incidence is independent of ethnic background, race, geographic location, gender, or any other environmental factors. Some adults develop one leg bone that is longer than the other, requiring a shoe lift for stability. Fractures are more common in adolescents, but some adults develop one leg bone that is longer than the other.
Nasal polyps are benign growths in the sinus cavity that may obstruct breathing and cause severe congestion, as well as cancer and blindness. They’re treated with surgery and a cast. To prevent fractures and chronic discomfort, operations are done to remove bone spurs, which can be painful over time.
Effects of cannabinoids on fibrous dysplasia
The plant has anti-inflammatory, antioxidant, and pain killing properties. It works as a CB1 and CB2 modulator, preventing treatment-resistant inflammation and chronic pain by acting on central nervous system immune cells and neurotransmitters, which it does via the modulation of inflammatory cytokines.
Medical cannabis, on the other hand, may help to decrease inflammation, making it even more beneficial for Inflammatory fibrous hyperplasia. CB1 and CB2 cannabinoid receptors are present in neurons and immune system cells, according to Future Science.
CB1 and CB2 receptors have also been discovered on immune cells in the study, suggesting that cannabinoids play a critical role in the management of the immune system. “Furthermore, both CB1 and CB2 receptors have been identified on immune cells, implying that cannabis has an important role in the regulation of the immune system,” according to the research.