Medical cannabis for patients with Lennox-Gastaut syndrome
Lennox-Gastaut Syndrome is an uncommon and severe form of epilepsy that begins in early childhood. According to the US National Library of Medicine Genetics Home Reference, the condition includes a variety of convulsive seizures. The most frequent type of tonic seizure happens when the muscles stiffen up during sleep and wakefulness, and there are drop assaults, which are sudden loss of muscle tone that might result in severe falls and damage.
Medical marijuana is an effective treatment for epilepsy, and a recent study showed that it may also be an effective treatment for Lennox-Gastaut Syndrome (LGS). The FDA has even approved a drug made from medical cannabis to treat this condition. This approval serves as a reminder that developing sound medical therapies based on active ingredients in marijuana can lead to important medical breakthroughs.
The commissioner also stated, “The FDA is dedicated to this type of meticulous scientific research and drug development,” as well.
Symptoms, Causes, and Treatment of Lennox-Gastaut Syndrome (LGS)
LGS might be caused by a variety of factors, according to the U.S. National Library of Medicine, although it can also result from an existing neurological condition that occurred during pregnancy when the brain grows. Some specific reasons mentioned by WebMD include lack of oxygen during delivery, cortical dysplasia, tuberous sclerosis, and brain infections.
Medical marijuana is becoming an increasingly popular treatment for a variety of medical conditions, including epilepsy. The National Organization for Rare Disorders (NORD) reports that the condition occurs in .1-.28 people per 100,000, possibly accounting for 1-4% of childhood epilepsy diagnosis. Symptoms of Lennox-Gastaut are the presence of all types of convulsions, including tonic, atonic, and absence seizures. Epidiolex, a cannabidiol FDA-approved drug, is the first prescribed medicine for this condition.
Medicinal cannabis and Lennox-Gastaut syndrome
Epidoloex, like Epidoloex, appears to have beneficial effects on other seizure types, specifically epilepsy. Even the Epilepsy Foundation has acknowledged it, based on a 2018 New England Journal of Medicine study entitled “Cannabidiol Effects On Drop Seizures In Lennox-Gastaut Syndrome.”
When combined with conventional antiepileptic therapy, cannabidiol reduced drop seizures in adults and children with Lennox-Gastaut syndrome by 10 or 20 mg per kilogram of body weight per day.
LGS is a rare and severe form of epilepsy that begins in childhood. There is no cure for LGS, but there are treatments that can help lessen the symptoms. Some people with LGS find that medical cannabis helps reduce their seizures. Medical cannabis is not a cure, but it can help to reduce the number of seizures, for someone, with LGS experiences.
According to the Motley Fool, “GW is conducting a late-stage clinical trial in the USA with the goal of getting FDA approval. It’s also doing phase 1 and phase 2 studies on cannabinoids intended to treat diseases such as autism spectrum disorders, schizophrenia, and epilepsy.”
The future for medical cannabis and LGS appears to be getting brighter, as more and more people become aware of the plant’s advantages. Meanwhile, children suffering from LGS do not have to live in agony any longer, thanks to the FDA-approved Epidolex, which demonstrates that CBD may cure depilatory disease.